Molecular biology
DEFINITION:
The study of the structure, function and makeup of the
molecular building elements of life is known as molecular biology.
EXPLANATION:
It focuses on the interactions between a cell's numerous
processes, such as the interplay between DNA, RNA, and protein synthesis, and
how these relationships are controlled. Molecular biology, the most recent of
the biosciences, is closely linked to biochemistry, genetics, and cell biology.
Molecular biology dates back to the 1930s when scientists
sought to understand life's phenomena by examining the macromolecules that make
it possible. Beginning in 1940, the breakthroughs in molecular biology occurred
over a 25-y25 years study of the structure, function, and makeup of the
molecular building elements of life known as molecular biology. It focuses on
the interactions between a cell's numerous processes, such as the interplay
between DNA, RNA, and protein synthesis, and how these relationships are
controlled. Molecular biology, the most recent of the biosciences, is closely
linked to biochemistry, genetics, and cell biology. Molecular biology dates
back to the 1930s when scientists sought to understand life's phenomena by
examining the macromolecules that make it possible. Beginning in 1940, the breakthroughs
in molecular biology occurred over 25-ye25 years standing how molecules conduct
metabolism, or how they process the energy required to sustain life, was
another significant breakthrough. Molecular biologists may now investigate
higher plants and animals using genetic engineering techniques, which opens up
the possibility of modifying plant and animal genes to increase agricultural
productivity. These techniques also paved the path for gene therapy to take
off.
With the start of the now-completed Human Genome Project in
1990, an ambitious international endeavor in molecular biology began (HGP). Its
mission was to find all 20,000 to 25,000 human genes and make them available
for further scientific research.
Another goal of the study was to decipher the entire sequence
of the three billion DNA components (bases in the human genome). Parallel
studies on selected model species such as the bacterium E. coli and the mouse
were conducted as part of the HGP to aid in the development of technology and
the interpretation of human gene function. The HGP was co-sponsored by the
Department of Energy Human Genome Program and the National Human Genome
Research Institute of the National Institutes of Health.
MOLECULAR BIOLOGY
SUBDISCIPLINES
Genomics Comparative
This is the study of human genetics through comparisons with
model organisms including mice, fruit flies, and E. coli bacteria.
DNA Forensics is a branch of forensic science that
deals with the study
This is when DNA is used to identify someone. The use of DNA
in child support disputes, establishing paternity, establishing the presence of
a suspect at a crime scene, and identifying accident victims are just a few
instances.
Functional Genomics is a branch of genomics that studies
how
This is the study of genes, the proteins that they produce,
and the role that proteins play in the biochemical processes of the body.
Gene Therapy is a type of gene therapy that
involves
This is a process for replacing, modifying, or augmenting
nonfunctioning or misfunctioning genes with healthy genes in an experimental
setting.
Genomics
The study of genes and their functions is referred to as
genetics.
Genetics at the
molecular level
The study of macromolecules that play a role in biological
heredity.
Pharmacogenomics
This is the study of how a person's genetic composition
interacts with their pharmacological reaction.
Proteomics
This is the study of a genome's complete set of proteins.
Structural Genomics is
a branch of genomics that focuses on the structure
This is a project that aims to discover the three-dimensional
structures of a large number of proteins using both experimental and computer
simulation techniques.
Toxicogenomic
This is the study of how genomes react to stressors or
toxicants in the environment.
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